HCG after IVF: dynamics, when you should do analysis, can it be erroneous, reviews are women's advice

The results of the HCG analysis after IVF are important for every woman after this procedure. Read in the article how the dynamics occurs, what are the norms for weeks and other useful information.

Contents

Implantation - This is the result of the work of many mechanisms that occur simultaneously in a timely synchronized scheme. As the embryo moves in a blastocyst, a decidualized endometrium, it develops to a receptive phenotype.

Read on our website an article about blood test for hCG - on what day it should be taken, how to prepare. You will also find a lot of other useful information.

Embryo implantation - a complex process that includes constant molecular cross exchange between the embryo and the decidual shell. One of the key molecules in this process is human chorionic gonadotropin (hCG). It effectively modulates several metabolic pathways in the decidual shell, contributing to the susceptibility of the endometrium. This article describes what is the dynamics of growth, or vice versa, a decline in hCG and why. You will also learn when to take an analysis for hCG after IVF, and whether it can be erroneous. Read further.

The role of analysis and dynamics of hCG growth during pregnancy after IVF: FACTS AND Science

Human chorionic gonadotropin (hCG) - The hormone produced by the cells of the trophoblast of the placenta. It can reflect the mass of trophoblast and is the earliest affordable marker to assess the progression of pregnancy. What is the role of analysis and dynamics of hCG growth during pregnancy after IVF? Here are the facts and what the science says:

Shortly after implantation, the hCG level increases dynamically and can already be detected after 6-8 days in blood serum Mother.
In addition to the fact that it serves as an indicator for assessing the progression of pregnancy, hCG in the early stages show several other physiological functions for the development of the embryo.
In addition to its main role in maintaining the yellow body, the “hormone of pregnancy” also plays a decisive role in the proliferation of trophoblasts and angiogenesis, thereby facilitating the development of the placenta.

Several studies of scientists from different countries of the world revealed a connection between the low level of hCG in the mother and the risk of adverse outcome of pregnancy. Other researchers have found that the lower level of hCG in the maternal serum on 12th day After the embryo was transferred, he was an independent predictor of severe preeclampsia. They also said that increasing the level of hCG at the very beginning of the first trimester was associated with a decrease in the weight of the newborn at birth. All these data indicate that HCG is an important indicator of the outcome of pregnancy.

The answers to the stimulation of the ovaries were very different in different women, even of the same age during extracurporeal fertilization and the transfer of the embryo (eco-et). Read more:

The decrease in the ovary reserve (DOR) is used to characterize this variation, and is determined by how women of reproductive age respond to ovarian stimulation compared to other people of the same age.
A single definition of a reduced ovary reserve (DOR) is currently not available.
Most studies demonstrate that FSG ›10 IU / L can reflect Dor.
In addition, AFC and AMH can also reflect Dor. However, threshold values \u200b\u200bremain vague.
The FSG is secreted by the anterior pituitary gland and contributes to the development of follicles, and the increase in FSH can be the result of a decrease in the number and quality of antrol follicles.
A decrease in the number of antral follicles (AFC) leads to a decrease in estradiol (E2) and inhibin B. This process can weaken the negative feedback of the follicle -stimulating hormone (FSH) and subsequently reduce the level of FSH.

Therefore, the FSG can be considered as a marker for evaluating the ovarian reserve. As you can see, there are a lot of factors affecting the concentration of hCG in the mother in the early stages of pregnancy in IVF. All this is difficult, but you can understand. Now let's look in detail what the HCG level should be after IVF. Read further.

What hCG to take after IVF - general or free?

After IVF, it is necessary to take a general analysis of hCG. It will help to notice the pregnancy at the earliest stage, even before it can determine the ordinary test strip from the pharmacy. The free indicator of this hormone is not so informative.

HCG Table for DPP (days after transferring, landing) IVF - standards in the early stages: 1, 2, 5, 12, 14 day

The biochemical cross dialogue between the embryo and the decidual shell, installed in the “interface” of the mother and fetus, occurs synchronously. The embryo before implantation secreists factors that can modulate the implantation. On the other hand, the decidual shell secrete cytokines and growth factors that affect embryonic differentiation and early development. HCG here plays the role of an intermediary who interacts with important systems of the female body.

CHG Table for DPP (days after transferring, landing) IVF with standards in the early stages - 1, 2, 5, 12, 14 day, etc.:

HCG Table for DPP (days after transferring, alignment) IVF - standards in the early stages

It is worth noting that the table begins with 7th day, because on 1-5 days There are almost no changes.

Important: If you notice any deviations in your indicators compared to the table, then you should immediately consult a doctor.

HCG table for pregnancy weeks after eco

It has already been said above that in the corresponding biochemical environment of the female body, the components of the embryo and endometrium interact for the invasion of trophoblast. One of the molecules of the source array of molecular messages between the blastocyte and the decidual shell is human chorionic gonadotropin (hCG)which is a marker of pregnancy.

This table contains data on the concentration of hCG by weekend weekend after IVF:

Remember: Table indicators are the norms of a separate laboratory. Hormone indicators, if you donate blood in another diagnostic center, may vary. Only the doctor should interpret the results.

Also, if you notice deviations and the difference between your indicators and tabular, then it is better to contact your gynecologist.

Dynamics - a positive or negative result in the analysis of hCG after IVF: on what day is the growth of indicators?

The dynamics is important, since conclusions are drawn on it regarding whether the embryo will take root or not. The result in the analysis of the hCG after IVF will be either positive or negative. So, on what day can a good increase in HCG levels after the transfer of the embryo?

If the transfer of embryos was carried out after 2 days after extracting, and the first pregnancy test was assigned 12 days later (14 days after extraction), then what turns out:

The average concentration of hCG will be approximately 126 mm/ml With a viable pregnancy and 31 mm/ml With non -viable - four times higher.
The average hCG level during pregnancy will be almost twice as high as with a single -exchanging - 201 MME/ml versus 115 mm/ml.

Thus, we can say with the confidence that the level of hCG 76 mm/ml will be a suitable cutting point for forecasting a viable pregnancy with 80% sensitivity and 82% specificity. The predictive value of a positive result for a viable pregnancy at this level will be 87%, and the prognostic value of the negative result - 74%.

Methods for determining the concentration of hCG after IVF: in urine, blood

HCG growth after IVF usually begins after 5 days After the transplant. The maximum value of hCG hormone is achieved approximately on 10-11 days After the procedure. After that, a slow decrease in the hormone level in the body occurs.

The concentration of hCG after IVF is determined by two methods:

Blood analysis
Analysis of urine

Among women, the second method is most common, because The test strips are relatively inexpensive, and they can be purchased at any pharmacy. A blood test can only be done in the laboratory, and more often this procedure is paid, especially if it is carried out independently - without the appointment of a doctor.

When should I analyze hCG after IVF?

Doctors recommend doing analysis for hCG after eco on 10-14 days After the transfer. If you make a test too early, then it may turn out to be negative, which will cause a negative reaction in a woman and can lead to serious problems. Psycho -emotional stress during pregnancy has a negative effect on the health of the baby, so it is better to wait two weeks, and then take the analysis.

Can an analysis for hCG be erroneous?

Any pregnancy test, even the most accurate, may be wrong. Here are a few reasons why the test can show a false-negative result:

The test was carried out too early. As mentioned above, you should not do a pregnancy test before 10-14 days.
You came across a defective test. In this case, it is recommended to purchase several tests of different brands.
Individual characteristics of the body of a woman.

Can an analysis for hCG be mistaken? Unlike test strips, a blood test for the “hormone of pregnancy” is more accurate and the probability of error is very low. We can say that laboratory tests are never mistaken. But it is worth repeating that each laboratory has its own values.

Remember: All the results that are given in the tables above are an average indicator. To find out the exact result, you must consult your doctor.

When is the first ultrasound for hCG after IVF?

There are times when a gynecologist prescribes an ultrasound examination. When is the first ultrasound for hCG after IVF?

Ultrasound is necessary only in special cases.
For example, if hCG indicators are too low. Ultrasound is prescribed in order to check the condition of the embryo at the moment.
If an ectopic pregnancy began to develop, then it can be confirmed using ultrasound.

If after the diagnosis the problem of low hCG remains, then it is necessary to look for another reason for this condition. Contact your doctor who observes pregnancy.

How does the level grow: if hCG grows slowly after IVF, what does this mean?

Do not worry if the level of concentration of hCG in the body grows after IVF too slowly. In some cases, this is one of the options for the norm. What does it mean?

Causes of slow growth hCG:

The presence of chronic diseases
Functional insufficiency of the thyroid gland
Individual characteristics of the body

In any case, it is better to consult your doctor, he will be able to determine the exact cause of the slow growth of hCG.

High hCG after IVF: what does this mean?

Naturally, the woman, after the procedure, is worried about any reason regarding her health. Especially if the hCG level is high. What does it mean?

Important do not understand these numbers literally.
There are many variables that can affect the values \u200b\u200bof hCG, including the analysis used.
The embryo transfer day also matters. HCG levels differ for transfer to the third and fifth day.

In any case, it is better to contact a specialist who will help with resolving this issue and interpretation of the results.

A sharp decrease in hCG levels in tests during pregnancy after eco

It is necessary to track the level of hCG concentration in analyzes during the first trimester of pregnancy, especially after IVF. All this is necessary in order in the case of an unforeseen situation, to help a woman in time. The risk of termination of pregnancy is high in this period.

If the hormone level decreases sharply, then doctors suspect either a frozen or ectopic pregnancy. Sharp leaps in the concentration of hCG - the reason why the woman can be sent to the hospital for preservation.

It is important to understand: For the reliability of the data obtained, it is necessary to take tests in the same laboratory.

If necessary, the woman will be prescribed treatment and the chance to save the child will be increased.

When are the drugs: when do hCG injections after IVF?

The doctor prescribed drugs to increase hCG and preserve pregnancy

To avoid termination of pregnancy, hormonal drugs are used to support the female body.

Progesterone-containing drugs They will have a positive impact on the process of embryo development. This substance supports the endometrium in such a state that the embryo is easily implanted into its uterine thickness.
The doctor may also prescribe estrogen-containing drugs. They also support the female body and stimulate metabolic processes.

Remember: It is forbidden to prescribe drugs yourself! Only the attending physician should do this. He will choose the necessary drugs based on the individual characteristics of the patient's body.

The duration of taking drugs on average about 10-12 weeks. Then it is necessary to gradually reduce the level of concentration of hormones until completely cancel.

When is the hCG injection after IVF? The appointment of hormones injections individually in each case as well as when prescribing drugs. Many women are appointed on the day of transfer, then every other day and again every other day. After such a treatment regimen, hCG is more than 2000 mm/ml per 14 dp.

Sensations with increasing indicators: signs of pregnancy with hCG after eco

Sensations with increasing hCG indicators

Of course, after the transplantation in the woman’s body, some changes begin. They can influence general health. These sensations are very noticeable with increasing hCG. Here are the signs of pregnancy after IVF:

Dizziness
Constant drowsiness and fatigue
General ailments - nausea, etc.
Light pulling pain in the lower abdomen

In fact, there is no exact set of signs of pregnancy at hCG after IVF. All of the above symptoms can occur due to other causes. An evil joke in this case can also play self -hypnosis. If you have any questions about your well-being, contact a gynecologist for advice.

HCG with double after eco

Although a higher number of hCG may indicate the conception of twins, this is not 100% guarantee of multiple pregnancy. As discussed above, there are many other reasons why you may encounter a higher level of hCG concentration after IVF. Therefore, in order to determine whether you are pregnant with twins or not, you need to do an ultrasound examination.

It is worth knowing: Twins can be found on ultrasound in 6 weeks After conception.

In addition to the higher level of hCG during pregnancy, if you are pregnant with twins, you may also face such conditions

Strong nausea
An increased feeling of fatigue
Quick weight gain

Of course, these signs do not give a complete guarantee that you will have twins. As mentioned above, for reliability, it is necessary to carry out the procedure of ultrasound.

HCG growth during cryoprotocol

Cryoprotocol is the seal of frozen embryos. This is done in order to increase the survival of the fetal egg. The growth indicators of the concentration of hCG in the body are growing in accordance with the gestational age.

Possible problems when determining hCG after IVF: List

When determining hCG after IVF, do not take drugs and drink a lot of water

Sometimes problems arise when determining hCG after IVF. Typically, such problems appear due to the inconsistency of the hormone level indicators, when conducting an analysis in different ways.

Ultrasound and analysis may not correspond

Conditions in which such situations may arise - a list:

The study was conducted too early.
Different dates of diagnosis.
Individual characteristics of the body.
The use of different drugs, for example, diuretics or the use of a large amount of water.
The presence of pathologies.

In the future, to prevent problems from arising, it is better to take a blood test, not to change the attending physician and perform analyzing in one laboratory.

Lifestyle after a positive result of hCG after eco

After conducting a pregnancy test and its positive result, a woman should correct her lifestyle a little. This will help to avoid problems with your own health, as well as the health of the future baby. This is what a lifestyle should be after a positive HCG result after IVF:

Do not do too active sports, and also avoid excessive physical exertion.
Exclude stress from your life.
Observe bed rest in the first day after IVF.
Lead a healthy lifestyle.
Take hormonal drugs prescribed by the doctor.

Pay attention to the fact that you need to eat as many vitamins as possible:

Calcium:

Main sources: milk, cheese, yogurt and sardins.
During pregnancy, you need 1000 milligrams (mg) per day.

Vitamin A:

You need this vitamin for healthy skin, vision and bone growth.
Carrots, dark, leaf greens and sweet potatoes are good sources.
During pregnancy, you need 770 mcg per day.

Vitamin C:

It helps to strengthen the health of gums, teeth and bones, and also helps your body absorb iron.
Good sources: citrus fruits, broccoli, tomatoes and strawberries.
During pregnancy, you need 85 mg per day.

Vitamin D:

Helps the body in the absorption of calcium to help build the bones and teeth of the unborn child.
Sources: exposure to sunlight, oily (preferably home) milk and fat fish, such as salmon.
During pregnancy, you need 600 mcg per day.

Vitamin B6:

Helps to form red blood cells and helps the body absorb protein, fats and carbohydrates.
You can find vitamin B6 in beef, liver, pork, whole -grain flakes and bananas.
During pregnancy, you need 1.9 mg per day.

Vitamin B12:

Helps to form red blood cells and supports the nervous system.
This vitamin can only be found in animal products.
Good sources: liver, meat, fish, poultry and milk.
During pregnancy, you need 2.6 mg per day.

Folic acid:

Important for the production of blood and protein, also reduces the risk of defects in the nervous tube (congenital defect of the brain and spinal cord).
Folic acid can be found in green, leafy vegetables, liver, orange juice, legumes (beans, peas, lentils), nuts.
It is necessary to consume at least 400 μg of folic acid per day before pregnancy and during the first 12 weeks of bearing a child to reduce the risk of defects in the nervous tube.
During pregnancy, doctors recommend consuming 600 mcg per day.

Compliance with all of the above points will increase the chances of bearing and born of a healthy child.

Signs of pregnancy after IVF to hCG: List

Until the case of blood test at HCG, pregnancy can be determined by the following signs - the list:

Breast change:

This sign is one of the earliest.
The level of hormones in a woman quickly changes after conception. Due to their changes, the chest may swell.
The area around the nipples, called the Areola, can also darken.

Fatigue:

Feeling very tired - normal during pregnancy, starting from its beginning.
A woman can feel unusual fatigue a week after conception.
The causes are low blood pressure, low blood sugar.
If fatigue is associated with pregnancy, it is important to relax a lot.
The use of products rich in protein and iron helps to compensate for the loss of strength.

Nausea:

Such a morning disease is a known symptom of pregnancy.
But not every pregnant woman suffers from her.
The exact cause of the morning disease is unknown, but the hormones that pregnancy appear probably contribute to the appearance of this symptom.
Nausea can occur at any time of the day, but most often in the morning.

In addition, some women are disgusted by their favorite products. It is also associated with hormonal changes. There are times that nausea and new taste preferences last the entire pregnancy. But more often symptoms are reduced in many women approximately at the 13th or 14th week of pregnancy.

Delay:

The most obvious and early symptom of pregnancy, and what encourages many women to pass a pregnancy test is a delay in the menstrual cycle.
But not all delays are caused by an interesting position. In non -pregnant women, menstruation can be absent with different pathologies, as well as during the onset of menopause, which is also very early - at 35 years old.
There are also reasons, except for pregnancy, due to which menstruation disappears: a quick set or weight loss, hormonal problems, fatigue, stress.

Frequent urination:

In many women, this begins at about the sixth or eighth week after conception.
Such a symptom can be caused by an infection of the urinary tract, increasing blood sugar as a result of a change in the hormonal background, the use of diuretics, etc.

Constipation:

During pregnancy, a higher level of the hormone of progesterone can cause constipation.
Because of it, metabolism decreases, the intestines work worse and food passes through it slower.
To solve the problem, play sports, drink more water.

Mood swings:

They can appear, especially in the first trimester.
This condition is associated with changes in the hormonal background.

Headaches and pain in the back:

Many pregnant women report frequent light headaches, while others experience back pain.

Dizziness and fainting:

They can be associated with the expansion of blood vessels, a decrease in blood pressure and a decrease in blood sugar.

A pregnant woman can have several of these symptoms, or only one, two.

But it is worth remembering that a woman may have bleeding during pregnancy.

Important: If you are pregnant and you have health problems, consult your doctor about your condition, especially if you have bleeding. Only the doctor knows when it is normal, and when this is a sign of an emergency in terms of your health.

HCG analysis after IVF: reviews

Many women worry after the analysis of hCG after IVF. Some have too high indicators, others fall quickly. Read the reviews of other women who have been conducted by IVF.

Olga, 34 years old

I decided to share my happiness with you: finally I became pregnant. Eco went well! How many years I tried to have a child naturally, but it still did not work. My husband and I were just in despair: he wanted the heir, and I, too. For those who are interested in the question about the signs of pregnancy: I was sick and there was a terrible emotional instability. In one minute I cried, and in the other I laughed because of some nonsense. HCG was high after two weeks after the decoration. I hope that my review will help girls who want a baby, but can not decide on IVF.

Ekaterina, 26 years old

Despite the fact that I am young and seemed to be healthy, I could not get pregnant naturally. How much my young man and I did not try, everything is useless. Parents have already begun to worry that there was still no baby. Therefore, after a few years of unsuccessful attempts, I decided on IVF. The hCG was at first low, but then I was prescribed injections - the transfer of 1,500. It also drank the drugs prescribed by the doctor. Everything went well, gave birth to a healthy daughter. Girls, if you want a baby, then do not be afraid to do eco. Now medicine allows, and doctors are good: they will help, tell you, if that.

Anastasia, 37 years old

I had to resort to IVF for certain reasons, which I do not want to talk about. Everything went successfully: my son was born, who is now six months now. I want to say many thanks to the doctors who helped me throughout pregnancy. I even had to go to save once, hCG became too low. But everything worked out, the treatment of a gynecologist (Prandil, Hoogon) helped. I feel great at the moment. If you are afraid to do IVF, be sure to read more about this procedure and all fear will go away. I was also afraid at first, but then I decided all the same and I do not regret anything!

Video: Eco Pregnancy. How to increase the chances of pregnancy after IVF?

Video: 17 Day after transfer. HCG is growing eco

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